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This binding initiates an intracellular signaling cascade, promoting gene expression related to cell survival, proliferation, and migration, ultimately leading to the formation of new capillary networks and enhanced tissue perfusion

GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease

New England Journal of Medicine (NEJM) - "N Engl J Med

It is recognized that using a cut-off of 11.1 mmol/L after a 50 g GCT will result in a small number of women receiving an erroneous diagnosis of GDM (270)

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